Patients with a suspicion of NP-C should undergo a thorough and specific examination, including visceral, neurological and psychiatric assessments before being tested with laboratory analyses.

NP-C Suspicion index (NPC-SI):
The NP-C Suspicion Index is a simple-to-use tool that has been developed by a scientific commlittee to support physicians not familiar with the disease, in detecting NP-C among patients suspected as having the disease.

This index comprises ranked assessments of visceral, neurological and psychiatric signs and symptoms that are indicative to NP-C taking family history into account, to provide a risk prediction score for NP-C.

This score indicates whether a patient has a low probability of having NP-C or should be referred to a specialist centre for further evaluation. In children below 4 years of age, due to a low sensitivity , a prediction score below 70 may be not conclusive in this patient group.

A dedicated web site www.NPC-SI.com  is available to support physicians to automatically calculate the individual NP-C risk prediction score of their patients.

Moreover, the web site allows physicians to better understand the symptoms of the disease and how to detect specific abnormalities relating to NP-C.
Several patient videos focussing on specific disease symptoms such as Vertical gaze plasy, are available for this purpose.

 

US RESIDENTS

Please note that the information contained in this section of the website is not intended for US residents. Please visit our US webpage.

Please note that the information contained in this section of the website is not intended for US residents. Please visit our US webpage.

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