Development pipeline

Actelion's focus on high unmet medical needs

PhaseProduct/ CompoundIndicationStudyResults expected

IV

Bosentan

Combination bosentan & sildenafil in PAH

COMPASS-2

IV

Miglustat

Type 1 Gaucher disease patients switched from ERT to miglustat

MAINTENANCE

2010

III

Almorexant

Insomnia 

RESTORA

-

III

Clazosentan

Prevention of vasospasm-related morbidity / mortality post aneurysmal subarachnoid hemorrage (SAH)

CONSCIOUS-2
CONSCIOUS-3

H2 2010
2011

III

Macitentan

Pulmonary arterial hypertension

SERAPHIN

H2 2012 

III

Selexipag 

Pulmonary arterial hypertension

GRIPHON

-

II

CRTH2 antagonist

Asthma

II  

S1P1 agonist  

Multiple Sclerosis 

II

S1P1 agonist

Plaque psoriasis

-

II

Macitentan

Idiopathic pulmonary fibrosis (IPF) 

MUSIC 

I

Antibiotic 

Anti-infective

-

I

Cardiovascular

Cardiovascular 



 
 
 
 

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Lab Technician, Drug Discovery Pharmacology & Preclinical Development  

 

"One day the results of my work could help patients who currently have no treatment of their disease."