IV

Bosentan

Combination bosentan & sildenafil in PAH

COMPASS-2

2013

IV

Bosentan

Pediatric pulmonary arterial hypertension

FUTURE

2014

III

Macitentan

Pulmonary arterial hypertension

SERAPHIN

Complete

III

Selexipag

Pulmonary arterial hypertension

GRIPHON

2014

III

Macitentan

Digital ulcers associated with systemic sclerosis

-

2014

II

Cadazolid

Clostridium difficile associated diarrhea

-

Complete

II

Ponesimod

Multiple sclerosis

Complete

II

Ponesimod

Plaque psoriasis

Complete

I

Anti-malarial

Malaria

-

-

I

CRTH2 receptor antagonist

Asthma

-

-

I

Lucerastat

Lipid storage disorders

-

-

I

NCE

Immunological disorders

-

-

I

Macitentan

Glioblastoma

-

-

I

S1P₁ modulator

Immunological disorders